Progressive supranuclear palsy

Progressive supranuclear palsy (also known as PSP, or Steele-Richardson-Olszewski syndrome) is a rare degenerative disease, and is the most common atypical Parkinson-type movement disorder that affects movement, balance, and vision. Initially patients tend to lose their balance, resulting in unsteady walking, or abrupt and unexplained falls. The patients have a general slowing of movement, changes in personality, and visual symptoms. Later, they will suffer slurring of speech, dementia, difficulty in swallowing, and difficulty in moving their eyes, particularly in the vertical (downward) direction. Some present contracture of facial muscles, poor eyelid movements, and a backward tilt of head with stiffening of neck muscles.

Currently, there is no cure for PSP. Some medications may manage some symptoms temporarily. Cells treatment is a new therapeutic option for PSP.

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